A few notes from the article I linked to:
This post discusses medications used to treat MCAS. Doses listed are taken directly from “Presentation, diagnosis and management of mast cell activation syndrome” by Lawrence B. Afrin. These doses are general recommendations. Medication should always be taken under the direction of a provider who knows you and your case personally.
If you have Mast Cell Activation Disease (MCAD, also known as Mast Cell Activation Syndrome, MCAS) and need to have a surgery, here is the advice I received from the doctor/specialist who is treating me for MCAD/MCAS: “For patients such as yourself, I suggest continuing on antihistamines and taking prednisone (40 mg) the day before, the morning of, and soon after a procedure. Generally, the anesthesiologists and surgeons are fine with this.”