QZ.com published information about a scientific study to capture images of your brain on LSD. Quotes from the article:
“Nutt’s study ... was the first to use brain imaging to show the effects of LSD ... it showed that the drug weakens the rhythm of alpha brainwaves, which are known to be stronger in humans than other animals, and are considered a signature of high-level consciousness.”
“The study also found that LSD causes brain activity to become less coordinated in regions that make up the brain’s ‘default mode network,’ which is responsible for maintaining a stable sense of self. The greater the drug’s effect on the brain, the more participants experienced ego-dissolution, where the self melds with world around you.”
From the accompanying video: “LSD can also make people lose their sense of self ... as the higher-level network disintegrates, and normally estranged parts of the brain begin to interact, people’s thoughts and the outside world start to feel like the same thing.”